Mount Sinai School of Medicine
Biological and Biomedical Sciences
New York, New York 10029

Mt. Sinai School of Medicine


The mission of the School, is to provide a rigorous educational experience in biomedical sciences to excellent, research-oriented students, leading to the PhD and MD/PhD degrees. The educational approach provides you with a broad perspective, with the capacity and zest for mastering new knowledge in a period of ever more rapid change, and with the analytical skills that are fundamental to investigation. It also engages you in the broad institutional commitment of translating basic science findings into applications to human health. Innovative program and course design, and the full multidisciplinary use of institutional strengths in education and research attract a lively student group. The education programs are designed to foster your development into imaginative, independent investigators, including research-oriented physician-scientists, who will contribute significantly and in diverse ways to the progress of science.

There are currently 152 PhD students and 60 MSTP students matriculated in the Graduate School. Mount Sinai's growing research faculty is involved in numerous interactive and the newest areas of research. There are over 222 members of the Graduate Faculty who are eager to work with predoctoral students.

The Graduate School also sponsors a Summer Undergraduate Research Program (SURP) that selects a group of diverse undergraduate students (freshmen, sophomores and juniors) from across the country for a 10-week educational experience at Mount Sinai School of Medicine.

Mt. Sinai School of Medicine Campus in Manhattan

The Community
The Best Part of the Big Apple -- Mount Sinai is located on the Upper East Side of Manhattan (between Madison and Fifth Avenues). A beautiful part of Central Park is just outside our front door, providing inviting picnic, softball, and running opportunities. We are part of "Museum Mile", a stretch of Fifth Avenue that encompasses some of New York's most important art institutions. You can take advantage of Mount Sinai's superb Recreation Office to obtain tickets to numerous sports events, theatrical performances, concerts, and cut-rate restaurant opportunities. You can participate in community service and educational projects. The larger community of students in the New York Metropolitan area enhances your opportunities for enlarging perspective and scientific contacts while socializing.

Programs of Study
The Graduate Program offers education in diverse, cutting-edge areas of biomedically-important basic sciences in its PhD Program and MSTP (Medical Scientist Training Program, MD/PhD Program). The School has adopted a model for its predoctoral training that reflects the multidisciplinary nature of contemporary biomedical sciences. You are encouraged to pursue a course of study that focuses on rigorous mastery of the art, craft, and conceptual framework for an important research problem. You are sensitized to the broader biomedical context through the multidisciplinary core curriculum and training area organization.

Mt. Sinai Offers Individual Instruction

You matriculate without a formal commitment to a particular training area. While you may affiliate as closely as you wish with a group of researchers in your initial area of interest, you are† encouraged, by a strong advisory system, to consider new combinations or interests during your first year. You pursue a series of rotations through diverse research laboratories before formally choosing a PhD research mentor and one of six Multidisciplinary Training Areas -- Biophysical Structural Biology & Biomathematics; Genetics & Genomic Sciences; Mechanisms of Disease and Therapy; Molecular, Cellular, Biochemical & Developmental Sciences; Mount Sinai Microbiology; and Neurosciences. Within these MTAs, areas of research include cancer biology, endocrinology, enzymology, gene expression-transcription, gene therapy,immunobiology, mathematical modeling, molecular endocrinology, organellar biology-trafficking,pathobiology, peptide hormones, pharmacology, physical biochemistry, rational drug design, receptors, signal transduction-cell cycle, structural biology, systems physiology, transport channels/metabolism, and virology & oncogenes.

Facilities & Resources
The research facilities are housed primarily in the Annenberg and East Buildings. Throughout your graduate career at Mount Sinai, you can take advantage of the facilities of extraordinarily equipped laboratories including core facilities for special biophysical, molecular biological and immunological techniques. In addition, there is a superb library that offers ongoing opportunities for enhancement of computer skills.

Student housing is available in the Mount Sinai neighborhood. Our housing program enhances the sense of community among the different trainee groups within the institution and offers convenient access to labs, lectures, and special seminars throughout Mount Sinai.

Mt. Sinai Facilities and Resources

Expenses and Aid
Costs

Upon acceptance into the Program, you will be offered a fellowship package which consists of a stipend ($26,000), the full cost of tuition and a comprehensive health insurance package. Students with special needs can take advantage of loan and emergency funds.

How to Apply
Prior to matriculation, you should have received the BA or BS degree and completed a year of differential and integral calculus, a year of physics, chemistry through second semester organic chemistry, at least a year of biology, and at least one semester of biochemistry. In special instances, one or more of these courses can be taken just before or after matriculation. It is desirable for you to have taken some advanced science coursework. GRE scores (verbal,quantitative, analytical, and advanced) are also required for consideration. TOEFL is required if English is not your first language. Aside from the quality of undergraduate performance and the indications of general aptitude that are derived from the standardized test scores, the single most important criterion for acceptance into the PhD Program is evidence that you have those characteristics that lead to an independent and productive research career. Thus your exposure to research is of great interest to the Admissions Committee. You will be invited for an interview if you are under the most serious consideration for acceptance.

Who to contact
You may obtain application forms from our website:

(http://www.mssm.edu/gradschool/), download or email (grads@mssm.edu), or by calling our office at 212.241.6546.

The deadline for the receipt of all application materials is February 15, but early submission of applications is highly recommended for full competition of fellowships.

All application materials must be sent to:

Admissions Officer
Graduate School of Biological Sciences
Mount Sinai School of Medicine
Box 1022, One Gustave L. Levy Place
New York, NY 10029-6574
URL: http://www.mssm.edu/gradschool
Email: grads@mssm.edu
Tel: 212.241.6546 Fax: 212.241.0651

The Research Training Faculty
Aaronson, Stuart A., MD: Molecular genetics of cancer
Abramson, Ruth G., MD: Transporter/channel in intact cell membranes
Aggarwal, Aneel, PhD: Structural biology, DNA binding proteins
Astrin, Kenneth H., PhD: Somatic cell genetics and gene mapping
Bancroft, Carter, PhD: Signal transduction; DNA-based computation and cryptography Barka, Tibor, MD: Role of protooncogenes in cardiac tissues
Baron, Margaret, MD/PhD: Mammalian blood and vascular development
Bechhofer, David H., PhD: Regulation of bacterial gene expression
Benham, Craig J., PhD: Structure and transitions in DNA
Benson, Deanna L., PhD: Axonal guidance and synaptogenesis in CNS
Benson, Gary, PhD: Algorithm design for DNA sequence analysis
Bergemann, Andrew, PhD: Receptor tyrosine kinase
Berk, Paul D., MD: Non-insulin dependent diabetes mellitus
Bhat, Manzoor, PhD: Intercellular junctions; signal transduction, blood brain barrier
Bieker, James, PhD: Transcriptional regulation of red cell-specific gene expression
Bishop, David F., PhD: Biochemical/molecular genetics
Blaho, John A., PhD: Molecular virology, regulation of HSV replication
Blum, Mariann, PhD: Neurotropic factors
Bodian, Carol A., Dr.P.H.: Statistical problems in clinical and laboratory research
Bodnar, Richard J., PhD: Opioid and nonopioid forms of analgesia
Bona, Constantin, MD, PhD: Immunology/molecular immunology
Borden, Katherine L.B., PhD: RING proteins (promyelocytic leukemia protein)
Branch, Andrea D., PhD: RNA biochemistry and Therapeutics
Brannan, Timothy, MD: Parkinson's Disease
Brezina, Vladimir, PhD: Biological control mechanisms
Bromberg, Jonathan S., MD, PhD: Molecular and cellular transplantation immunobiology Bromme, Dieter, PhD: Cathepsin
Bruggeman, Leslie, PhD: Transgenic modeling of renal diseases & HIV-1 pathogenesis Burstein, David, MD: Cell differentiation
Candia, Oscar A., MD: Epithelial transport, water channels, membrane permeability
Caplan, Avrom J., PhD: Molecular chaperones and signal transduction
Cederbaum, Arthur, PhD,: Ethanol-induced oxidative stress and cytotoxicity
Chan, Andrew M.L., PhD: ras-related oncogenes in human cancer
Chen, Jia, ScD: Genetic Epidemeology: genetic susceptibility and gene-environment interactions in human diseases
Chen, Shu-Hsia, PhD: Cancer immunology
Claudio, Luz, PhD: in vitro model of the blood-brain barrier
Cohen, Bernard, MD: Neurophysiology
Cohen, Gerald, PhD: Neurochemistry
Coller, Barry S., MD: Platelet integrins
Colman, David R., PhD: Biosynthesis/assembly of myelin membrane proteins
Cropper, Elizabeth, PhD: Neural basis of behavioral plasticity in Aplysia
Cunningham-Rundles, Charlotte, MD, PhD: Antibody production in immunodeficient states
Davies, Terry F., MD: Autoimmune thyroid disease
Desnick, Robert J., PhD, MD: Biochemical/molecular genetics
Diverse-Pierluissi, Maria A., PhD: Integration of receptor-mediated signals
Eisensmith, Randy, PhD: Virally-mediated gene therapy for monogenic diseases
Elder, Gregory A., MD: Gene regulation of neurodegenerative diseases
Eng, Christine M., MD: Molecular genetics Fan, Jian-Qiang, PhD: Molecular therapy for genetic diseases
Fasy, Thomas, MD/PhD: Mutagenesis, assays for & mechanisms of novel cytokines
Fedi, Paolo, MD/PhD: Growth factor receptors in human cancer
Felsenfeld, Dan,PhD: Regulation of adhesion receptor function in axon growth and guidance
Fisher, Edward A., MD, PhD: Lipoprotein metabolism and atherosclerosis
Fishman, Glenn I., MD: Molecular genetics of cardiovascular disease
Flatow, Evan L., MD, Rotator cuff tendon failure; shoulder mechanics; shoulder replacement
Forrest, Douglas, PhD: Molecular genetics of thyroid hormone receptors
Frasch, Manfred, PhD: Gene expression during Drosophila embryogenesis
French, Deborah L., PhD: Integrins, platelet physiology
Frenette, Paul S., MD: Adhesion molecules in vascular biology
Friedman, Scott L., MD: Molecular regulation of hepatic fibrosis
Friedrich, Victor, PhD: Elaboration of myelin sheaths
Gannon, Patrick J., PhD: Evolution of language, paleoneurology research
Garcia-Sastre, Adolfo, PhD: Influenza virus vectors
Gelb, Bruce D., MD: Molecular cardiology
Gil, Juan, MD: Image analysis in pathology
Glucksman, Marc, PhD: Neurodegenerative diseases
Goldfarb, Mitchell, PhD: Growth factor signaling and embryological functions
Good, Paul, PhD: pathology, neurobiology
Gordon, Jon W., MD/PhD: Transgenic mice, age-related neurodegeneration
Gordon, Ronald E., PhD: Development of COPD and fibrosis atherosclerosis
Gore, Andrea C., PhD,: Reproductive neuroendocrinology
Grace, Marie E., PhD: Enzymology and gene expression
Greenberg, David A., PhD: Neurogenetics
Hall, Simon, MD: Gene therapy for prostate cancer
Haroutunian, Vahram, PhD: Neurochemistry, neuropathology, Alzheimer's disease
Harpel, Peter, MD: Thrombosis, atherosclerosis, cell receptors, endothelial cells
Healy, Dennis P., PhD: Molecular mechanisms of hypertension
Henderson, Scott, PhD: Functional organization of interphase nucleus
Herold, Betsy C., MD: Viral glycoproteins, cell surface receptors and HSV
Hirsch, Jeanne, PhD: G protein-mediated signaling in yeast
Hirschhorn, Kurt, MD: Cytogenetics
Hof, Patrick R., MD: Cortical connectivity in brain aging and dementia
Holstein, Gay R., PhD: Neurotransmitter & receptor studies of the vestibular systems Horvath, Curt M., PhD: Cytokines, growth factors, extracellular signaling polypeptides Huntley, George, PhD: Development and organization of cerebral cortex
Ioannou, Yiannis A., PhD: Molecular genetics
Iyengar, Ravi, PhD: Signal Transduction, G protein, drug design
Jepsen, Karl J., PhD: Skeletal fragility, aging of skeletal tissue
Johnson, Edward M., PhD: Environmental pathology
Kaplan, Ehud, PhD: Neurophysiology Keller, Gordon, PhD: Gene therapy
Keller, Gordon, PhD: Gene therapy
Kirchberger, Madeleine, PhD: Sarcoplasmic/endoplasmic reticulum Ca2+-ATPases (SERCAs)
Klotman, Mary E., MD: Molecular pathogenesis and therapy of HIV
Klotman, Paul E., MD: Pathogenesis and treatment of HIV associated nephropathy
Knott, Peter J., PhD: Neurochemistry
Kohanski, Ronald A., PhD: Insulin receptor kinase regulation
Kohtz, D. Stave, PhD: Cardiac pathology
Krauss, Robert S., PhD: Cancer, oncogene, cell cycle, cell differentiation
Kretzschmar, Marcus, PhD: Signal transduction and gene regulation, TGEB family growth factors
Krulwich, Terry Ann, PhD: Tetracycline and Na+ transporters; oxidative phosphorylation Laitman, Jeffrey T., PhD: Vocal tract development
Landau, Emmanuel M., MD: Electrophysiology
Laws, William R., PhD: Protein-protein interactions
Lazarow, Paul B., PhD: Yeast peroxisome biogenesis/inherited human diseases
Linden, R. Michael, PhD: DNA integration into the human genome, gene therapy Logothetis, Diomedes, PhD: G protein activation of potassium channels
Lou, W.Y. Wendy, PhD: Distribution theory of patterns, DNA sequence analysis
Lufkin, Thomas, PhD: Development of vertebrate embryonic body plan
Maayani, Saul, PhD: Membrane receptors and effectors
Majeska, Robert J., PhD: Bone cell biology; skeletal development & repair
Mandeli, John P., PhD: Statistical design and analysis of experiments
Manfredi, James J., PhD: Regulation of p53 tumor suppressor activity
Margolskee, Robert, MD/PhD: Sensory transduction, molecular neurobiology
Martignetti, John A., MD, PhD: Tumor suppressor genes
Masur, Sandra K., PhD: Regulation of cells and the extracelluar matrix
Max, Marianna, PhD: Circadian rhythms
Mayer, Lloyd F., MD: Immunobiology, B cell differentiation, cytokine regulation
McGinnis, Marilyn Y., PhD: Mechanisms of androgen action in brain
McGovern, Margaret M. MD, PhD: Molecular diagnostics
Mehler, Ernest, PhD: Molecular biophysics
Mezei, Mihaly, PhD: Monte Carlo computer simulations, water structure
Mira-y-Lopez, Rafael, MD, PhD: Aberrant vitamin A signaling in breast cancer
Marek , Mlodzik, PhD: Cellular interactions and signaling pathways in neuronal and epithelial patterning
Mobbs, Charles V., PhD: Age-correlated pathologies
Moran, Thomas, PhD: Immunology, T cell subsets markers
Morgello, Susan, MD: Pathology of HIV infection in the brain
Morrison, John Henry, PhD: Cortical organization, neurodegeneration, and aging Moscona, Anne, MD: Interaction between human viruses and the host cell
Mytilineou, Catherine, PhD: Developmental neurobiology
Najfeld, Vesna, PhD: Molecular cytogenetics
Nemerson, Yale, PhD: Biochemistry and molecular biology of clotting
Ng, Lily, PhD: Thyroid hormone receptor genes
Olanow, Warren C., MD: Putative neuroprotective therapies for Parkinson's disease Osman, Roman, PhD: Molecular biophysics
Ossowski, Lilliana, PhD: Proteases in cancer metastasis
Ouchi, Toru, PhD: Molecular basis for breast cancer development
Palese, Peter, PhD: Replication of RNA viruses, influenza viruses, antivirals, vaccines
Pan, Zhen-Qiang, PhD: Cycle controls
Pasinetti, Giulo M., MD/PhD: Molecular neuro-gerontology
Perl, Daniel P., MD: Neuropathology, Alzheimer's disease, Parkinson's disease
Pick, Leslie, PhD: Embryonic development and body pattern
Pinol-Roma, SerafËËn, PhD: Eukaryotic cell nucleus
Piperno, Gianni, D.Sc.: Motility of eukaryotic cells
Plevy, Scott, MD: Cytokines immunologic markers
Pogo, Beatriz G.-T, MD: Viral oncology
Rackovsky, Shalom, PhD: Theoretical studies of protein folding
Radu, Aurelian, PhD: Nucleocytoplasmic transport
Ramirez, Francesco, PhD: Molecular genetics, developmental genetics
Rapp, Peter, PhD: Learning and memory, the hippocampal system
Reidenberg, Joy S., PhD: Comparative anatomy of the respiratory/ vocal tract and skull Reinitz, John, PhD: Analysis of Drosophila pattern formation
Robakis, Nikolaos K., PhD: Neurodegeneration
Roberts, James L., PhD: Regulation of neuroendocrine gene expression and peptides Ronai, Ze'ev, PhD: Stress kinases, regulation of protein stability, radiation resistance Rosenstein, Barry, PhD: Radiation induced DNA damage and repair
Ross, J.B.A.(Sandy), PhD: Time-resolved spectroscopy of proteins
Sacks, Henry S., PhD, MD: Meta-analysis, decision analysis and cost-effectiveness analysis
Sadowski, Henry B., PhD: Receptor tyrosine kinase signaling
Salton, Stephen R.J., MD, PhD: Molecular neurobiology, growth factor signal transduction Sampson, Hugh A., MD: Immunopathogenic mechanisms
Sansaricq, Claude, MD, PhD: biochemical genetics and inborn errors of metabolism Sassaroli, Massimo, DSc: Fluorescence spectroscopy and cell imaging
Sassoon, David A., PhD: Cell differentiation, cell death, development, skeletal muscle Schaffler, Mitchell, PhD: skeletal biology, biomechanic, aging, osteoporosis
Schnapp, Lynn M., MD: Cell-extracellular matrix interactions
Schuchman, Edward H., PhD: Molecular genetics
Schulman, Jerome L., MD: Viral virulence, cellular immunology
Sealfon, Stuart C., MD: Structure-function and regulation of G-protein coupled receptors Shapiro, Lawrence, PhD: Structural biology of cell-cell adhesion
Shaw, Phyllis A., PhD: Regulation of cysteine proteinase inhibitor genes
Shneider, Benjamin, MD: Bile acid transport
Simonaro, Calogera M., PhD: Gene therapy for lysosomal storage disorders
Sirovich, Lawrence, PhD: Image analysis, fluids dynamics
Small, Gillian M., PhD: Regulation of peroxisomal proteins
Snoeck, Hans-Willem, MD, PhD: Stem cell biology, immunology, gene therapy, hematopoiesis
Sperber, Kirk, MD: Monocyte HIV-1
Suchy, Frederick J., MD: Basolateral and canalicular transporters for organic anions
Sudol, Marius, PhD: Signal transduction pathways
Sugar, Istvan P., PhD: Structure and function of lipid membranes and proteins
Sugrue, Mary M., MD, PHD: Tumor suppressor genes in pediatric tumors
Suzuki, Yasunosuke, MD: Lung cancer
Taneja, Reshma, PhD: Retinoic acid signaling pathway
Taubman, Mark B., MD: Control of vascular smooth muscle gene expression
Ting, Adrian T., PhD: Immunology and molecular biology
Tsai, Schwickmann, MD, PhD: Hematopoiesis, stem cell biology, gene therapy
Tulchin, Natalie, PhD: Mammary carcinogenesis
Unkeless, Jay C., PhD: Fc receptors and signal transduction
Wallenstein, Sylvan, PhD: Clinical trials, experimental design, epidemiology
Walsh, Martin, PhD: Cell cycle regulation and transcriptional control of human cells
Wang, Lu-Hai, PhD: Oncogenes, signal transduction and cell transformation
Warburton, Peter E., PhD: Chromosome structure, artificial chromosomes
Wassarman, Paul M., PhD: Mechanisms of fertilization in mammals
Weber, Thomas M., PhD: Development of non-viral gene therapy vectors
Weinstein, Daniel C., PhD: Molecular basis of verterbrate mesoderm induction and neural patterning
Weinstein, Harel, DSc: Computational molecular biophysics
Weiss, Klaudiuz R., PhD: Cellular and molecular neurobiology of behavior
Wetmur, James G., PhD: DNA recombination and repair; thermophilic proteins
Wilk, Sherwin, PhD: Proteolytic enzyme mechanism & function
Willner, Judith P., MD: Clinical genetics and teratology
Winckler, Bettina,PhD: Membrane traffic and membrane domains in polarized neurons
Wolosin, J. Mario, PhD: Gap junctions and differentiation in self renewing epithelia
Woo, Savio L.C., PhD: Gene therapy of metabolic disease and cancer
You, Guofeng, PhD: Structure/function of organic solute transporters
Zhao, Yingming, PhD: Functional genomics, proteomics, interaction proteomics, apoptosis, cancer
Zhou, Ming-Ming, PhD: Protein NMR spectroscopy, structural biology
Zier, Karen S., PhD: Tumor immunology, immunotherapy, and immunosuppression.

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